Hierarchical immunosuppression of regional lymph nodes in patients with head and neck squamous cell carcinoma.

@article{Wang1991HierarchicalIO,
  title={Hierarchical immunosuppression of regional lymph nodes in patients with head and neck squamous cell carcinoma.},
  author={Marilene B Wang and Alan K Lichtenstein and Robert A. Mickel},
  journal={Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery},
  year={1991},
  volume={105 4},
  pages={517-27}
}
Patients with head and neck squamous cell carcinomas (HNSCCs) manifest defects in cell-mediated immune function. Previous studies in this laboratory have demonstrated regional alterations in the immunocompetence of draining lymph nodes (LNs) in HNSCC patients. In this investigation, we studied functional activity of lymphocytes from lymph nodes in different locations in the radical neck dissections (RNDs) from patients undergoing operations for HNSCC. Lymphocytes from nodes close to the primary… CONTINUE READING

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