Hierarchical classification of functionally equivalent genes in prokaryotes

  title={Hierarchical classification of functionally equivalent genes in prokaryotes},
  author={Hongwei Wu and Fenglou Mao and Victor Olman and Ying Xu},
  booktitle={Nucleic acids research},
Functional classification of genes represents a fundamental problem to many biological studies. Most of the existing classification schemes are based on the concepts of homology and orthology, which were originally introduced to study gene evolution but might not be the most appropriate for gene function prediction, particularly at high resolution level. We have recently developed a scheme for hierarchical classification of genes (HCGs) in prokaryotes. In the HCG scheme, the functional… CONTINUE READING

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Detecting uberoperons in microbial genomes

  • D. Che, G. Li, F. Mao, H. Wu, Y. Xu
  • Nucleic Acids Res,
  • 2006
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HCG: A database for hierarchical classification of functional equivalent genes in prokaryotes

  • F. Mao, H. Wu, V. Olman, Y. Xu
  • Nucleic Acids Research,
  • 2006

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