Hierarchical Organization of Gamma and Theta Oscillatory Dynamics in Schizophrenia

  title={Hierarchical Organization of Gamma and Theta Oscillatory Dynamics in Schizophrenia},
  author={Kenji Kirihara and Anthony J. Rissling and Neal R. Swerdlow and David L. Braff and Gregory A. Light},
  journal={Biological Psychiatry},
BACKGROUND Schizophrenia patients have deficits across a broad range of important cognitive and clinical domains. Synchronization of oscillations in the gamma frequency range (~40 Hz) is associated with many normal cognitive functions and underlies at least some of the deficits observed in schizophrenia patients. Recent studies have demonstrated that gamma oscillations are modulated by the phase of theta waves, and this cross-frequency coupling indicates that a complex and hierarchical… CONTINUE READING


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