Hierarchical Evolution of the Bacterial Sporulation Network

@article{Hoon2010HierarchicalEO,
  title={Hierarchical Evolution of the Bacterial Sporulation Network},
  author={Michiel J.L. de Hoon and Patrick Eichenberger and Dennis Vitkup},
  journal={Current Biology},
  year={2010},
  volume={20},
  pages={R735-R745}
}
Genome sequencing of multiple species makes it possible to understand the main principles behind the evolution of developmental regulatory networks. It is especially interesting to analyze the evolution of well-defined model systems in which conservation patterns can be directly correlated with the functional roles of various network components. Endospore formation (sporulation), extensively studied in Bacillus subtilis, is driven by such a model bacterial network of cellular development and… CONTINUE READING