Hierarchical Bayesian Regression for Multi-Site Normative Modeling of Neuroimaging Data

  title={Hierarchical Bayesian Regression for Multi-Site Normative Modeling of Neuroimaging Data},
  author={Seyed Mostafa Kia and Hester Huijsdens and Richard Dinga and Thomas Wolfers and Maarten Mennes and Ole Andreas Andreassen and Lars Tjelta Westlye and Christian F. Beckmann and Andre F. Marquand},
Clinical neuroimaging has recently witnessed explosive growth in data availability which brings studying heterogeneity in clinical cohorts to the spotlight. Normative modeling is an emerging statistical tool for achieving this objective. However, its application remains technically challenging due to difficulties in properly dealing with nuisance variation, for example due to variability in image acquisition devices. Here, in a fully probabilistic framework, we propose an application of… 

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