Hidden hazards of HCV transmission

@article{Pond2010HiddenHO,
  title={Hidden hazards of HCV transmission},
  author={Rob{\'e}rio Amorim de Almeida Pond{\'e}},
  journal={Medical Microbiology and Immunology},
  year={2010},
  volume={200},
  pages={7-11}
}
  • R. Pondé
  • Published 1 February 2011
  • Medicine, Biology
  • Medical Microbiology and Immunology
Hepatitis C virus infection is a global health problem that has important epidemiological and clinical consequences. It has been well established that exposure to infected blood is the main risk factor for HCV transmission. However, in 20% of cases the agent transmission occurs by unknown route or in the presence of an unidentified source of infection. Understanding of the epidemiology of HCV is needed to help us define future control and preventive strategies. Herein, we discuss about… 

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References

SHOWING 1-10 OF 62 REFERENCES

Acute hepatitis C virus infection.

Concerns relating to acute HCV infection are highlighted and it is suggested that public health bodies responsible for managing the HCV epidemic should redirect at least some of their resources to dealing with these issues.

Transmission of hepatitis C virus in Asia: past and present perspectives

Until effective and safe immunoprophylaxis is available, interruption of transmission routes, such as implementation of blood donor screening for anti‐HCV, adequate sterilization of surgical instruments or the use of disposable medical instruments remains the mainstay to prevent HCV infection in Asia today.

High prevalence of hepatitis C virus infection among noninjecting drug users: association with sharing the inhalation implements of crack

Evaluated the prevalence of and factors associated with HCV infection among noninjecting drug users (NIDU) and found no identifiable source of HCV exposure.

Transmission of hepatitis C virus by blood transfusions and other medical procedures: a global review.

  • D. Prati
  • Medicine
    Journal of hepatology
  • 2006

Transmission of hepatitis C virus by saliva?

New experimental animal models and the recently described infectious HCV pseudoparticles, capable of simulating HCV replication in vitro, could be useful in establishing any role of saliva in the transmission of HCV infection.

[Hepatitis C virus. Iatrogenic and nosocomial transmition?].

The studies carried out in surgery units, support the idea that surgical acts are not involved in the HCV spreading, although they can be responsible for this transmission in specific occasions.

Studying Hepatitis C Virus: Making the Best of a Bad Virus

In most infected individuals, this remarkable RNA virus evades the immune system and establishes a chronic infection that can lead to cirrhosis, liver cancer, and death.

Perinatal transmission of hepatitis C virus infection

Maternal coinfection with HCV and human immunodeficiency virus, maternal history of intravenous drug use and of HCV infection of the sexual partner of the mother predict the risk of perinatal transmission and are dependent on the peripheral blood mononuclear cell infection by HCV.

Hepatitis C in France: A national survey in the departments of Internal Medicine and Infectious Diseases

A multicentre national prospective analysis of all positive HCV-antibody patients reported over a period of one month across France shows that Hepatitis C infection is a substantial clinical problem in French Departments of Internal Medicine and Infectious Diseases.

Acute hepatitis C virus infection: A chronic problem

The current information regarding the understanding of the epidemiology, virology, and immunology of HCV with a particular emphasis on acute HCV infection is reviewed and an algorithm for the diagnosis and management of acute HCv infection is proposed.
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