Hidden chromosomal abnormalities in pleuropulmonary blastomas identified by multiplex FISH

@article{Quilichini2005HiddenCA,
  title={Hidden chromosomal abnormalities in pleuropulmonary blastomas identified by multiplex FISH},
  author={Beno{\^i}t Quilichini and Nicolas Andr{\'e} and Corinne Bouvier and M. -A. Chrestian and Ang{\'e}lique Rome and Dominique Intagliata and Carole Coze and Gabriel L{\'e}na and H{\'e}l{\`e}ne Zattara},
  journal={BMC Cancer},
  year={2005},
  volume={6},
  pages={4 - 4}
}
Pleuropulmonary blastoma (PPB) is a rare childhood dysontogenetic intrathoracic neoplasm associated with an unfavourable clinical behaviour. We report pathological and cytogenetic findings in two cases of PPB at initial diagnosis and recurrence. Both tumors were classified as type III pneumoblastoma and histological findings were similar at diagnosis and relapse. In both cases, conventional cytogenetic techniques revealed complex numerical and structural chromosomal abnormalities. Molecular… CONTINUE READING
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