## 138 Citations

### Modelling Bacterial Genomes Using Hidden Markov Models

- BiologyCOMPSTAT
- 1998

This work compares different identification algorithms for hidden Markov chains and presents some applications to bacterial genomes to illustrate the method.

### Hidden Markov models in biology.

- Computer ScienceMethods in molecular biology
- 2010

In the course, the forward-backward, the Viterbi, the Baum-Welch (EM) algorithm, and a Metropolis sampling scheme are presented.

### A comparison of reversible jump MCMC algorithms for DNA sequence segmentation using hidden Markov models

- Computer Science
- 2001

A Bayesian approach to determining the number of hidden states in a hidden Markov model (HMM) via reversible jump Markov chain Monte Carlo methods, with particular emphasis placed on the comparison of the competing strategies in terms of computational expense, algebraic complexity and performance.

### Discussions on “A Bayesian Approach to DNA Sequence Segmentation”

- Computer Science
- 2004

A Bayesian method is described that identifies segments by using a Markov chain governed by a hidden Markov model to segmentation of the bacteriophage lambda genome, a common benchmark sequence used for the comparison of statistical segmentation algorithms.

### Discussions on “A Bayesian Approach to DNA Sequence Segmentation”

- Computer Science
- 2004

A Bayesian method is described that identifies segments by using a Markov chain governed by a hidden Markov model to segmentation of the bacteriophage lambda genome, a common benchmark sequence used for the comparison of statistical segmentation algorithms.

### Discussions on “A Bayesian Approach to DNA Sequence Segmentation”

- Computer Science
- 2004

A Bayesian method using Markov chain Monte Carlo techniques to compute all posterior quantities of interest and allow inferences to be made regarding the number of segment types and the order of Markov dependence in the DNA sequence is described.

### Discussions on “A Bayesian Approach to DNA Sequence Segmentation”

- Computer Science
- 2004

A Bayesian method using Markov chain Monte Carlo techniques to compute all posterior quantities of interest and allow inferences to be made regarding the number of segment types and the order of Markov dependence in the DNA sequence is described.

### A Bayesian Approach to DNA Sequence Segmentation

- Computer ScienceBiometrics
- 2004

A Bayesian method that identifies segments of similar structure by using a Markov chain governed by a hidden Markov model is described, applied to the segmentation of the bacteriophage lambda genome.

### Detecting homogeneous segments in DNA sequences by using hidden Markov models

- Biology
- 2000

A Bayesian solution to this segmentation problem is presented using a hidden Markov model implemented by Markov chain Monte Carlo methods and an intron from the chimpanzee α‐fetoprotein gene is studied.

### Bayesian Restoration of a Hidden Markov Chain with Applications to DNA Sequencing

- Mathematics, Computer ScienceJ. Comput. Biol.
- 1999

This work presents a Bayesian solution to the problem of restoring the sequence of states visited by the hidden Markov chain from a given sequence of observed outputs through the Bayesian approach to HMM restoration.

## References

SHOWING 1-10 OF 21 REFERENCES

### Stochastic models for heterogeneous DNA sequences.

- MathematicsBulletin of mathematical biology
- 1989

### Theoretical models for heterogeneity of base composition in DNA.

- BiologyJournal of theoretical biology
- 1974

### Sequence and organization of the human mitochondrial genome

- BiologyNature
- 1981

The complete sequence of the 16,569-base pair human mitochondrial genome is presented and shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs.

### The genome of simian virus 40.

- BiologyScience
- 1978

The nucleotide sequence of SV40 DNA was determined, and the sequence was correlated with known genes of the virus and with the structure of viral messenger RNA's. There is a limited overlap of the…

### Statistical characterization of nucleic acid sequence functional domains.

- BiologyNucleic acids research
- 1983

This report investigated the statistical measures most distinctive of the various domains of the genome and then linked them to current understandings in so far as possible and suggested others.

### Giant G+C% mosaic structures of the human genome found by arrangement of GenBank human DNA sequences according to genetic positions.

- BiologyGenomics
- 1990

### Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome.

- BiologyJournal of molecular biology
- 1982

### CpG-rich islands and the function of DNA methylation

- BiologyNature
- 1986

It is likely that most vertebrate genes are associated with ‘HTF islands’—DNA sequences in which CpG is abundant and non-methylated. Highly tissue-specific genes, though, usually lack islands. The…