Hiccups as a myocardial ischemia symptom.

  title={Hiccups as a myocardial ischemia symptom.},
  author={Waldemar Krysiak and S. Szabowski and Marta Stępień and Katarzyna Krzywkowska and Artur Krzywkowski and Piotr Marciniak},
  journal={Polskie Archiwum Medycyny Wewnetrznej},
  volume={118 3},
A hiccup is involuntary, paroxysmal inspiratory movements of the chest wall associated with diaphragm and accessory respiratory muscle contractions, with the synchronized closure of glottis. The mechanism underlying this common primitive reflex plays an important role in protecting airways against esophageal aspiration. The hiccup reflex mechanism is based on the afferent pathway (vagus and phrenic nerve and sympathetic fibers innervating chest organs, the abdomen, the ear, the nose and the… 

Hiccup: Mystery, Nature and Treatment

Hiccup is likely to result from lesions involving the hiccup reflex arc, and drugs acting on reflex arc may be effective, while some other conventional measures may also be tried.

Pesky Hiccups; May be Risky!

A case of intractable hiccups in a 67 y/o male as the initial symptom of coronary heart disease and the delay in treatment had affected his chances of survival, and his hiccuping symptoms had recurred and persisted and he died after two months from the time of diagnosis.

Hiccups as a Sign of Chronic Myocardial Ischemia

Two unusual presentations of myocardial ischemia in patients whose main symptom was hiccups are described, the first intractable hiccup over months and the second effort-induced hiccup, both of which also described atypical chest pain.

Chronic Hiccups

The pathophysiology of hiccups including multiple causes and the appropriate work up for each is reviewed, including several studies examining new treatments, both pharmacological and interventional, that may help patients.

Myocardial Ischemia Presenting with Hiccups.

  • S. Yuan
  • Medicine
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • 2019
Of the therapeutic regimens, gabapentin is a second-line agent alternative to baclofen in treating hiccups and is especially helpful in patients undergoing stroke rehabilitation or palliative care when chlorpromazine is prohibited due to its adverse effects.

Acute Coronary Syndrome Presenting With Hiccups

This is the first reported case in which hiccups were a part of the primary symptoms associated with severe triple vessel coronary artery disease and the importance of having a high index of suspicion is stressed, especially among high-risk and elderly patients.

Persistent Hiccups as the Only Presenting Symptom of ST Elevation Myocardial Infarction

A 74-year-old male with a past medical history of type 2 diabetes mellitus, hypertension, hyperlipidemia, and COPD due to chronic tobacco use, who presented with persistent hiccups for 4 days and no other complaints is investigated for an underlying cardiac etiology.

Acute proximal left anterior descending thrombosis manifested by persistent hiccups

Hiccup is only rarely described in the context of acute proximal LAD thrombosis, however, if this special symptom occurs intractably during disease progression, thrombus is revealed to be the probable cause, prompt opening of the criminal vessel should be performed besides strengthening of anticoagulant and antiplatelet.

Sobbing: phonotherapeutic characteristics and possibilities

It is concluded that sobbing may occur in view of the neurological pathologies, gastrointestinal, thoracic and/or toxic metabolic profiles, and a possible phonoaudiological therapeutic approach.

Persistent Hiccups after Switching from Zuclopenthixol to Aripiprazole

A patient of 66 year-old male with late-onset schizphrenia who developed persistent hiccups with switching from zuclopenthixol to the atypical antipsychotic aripiprazole is reported, and the possible underlying neurotransmitter mechanisms and the clinical implications are discussed.



Intractable hiccuping in acute myocardial infarction.

Though pancreatic ascites has resolved after conservative management and after diagnostic laparotomy, the rapid cessation of pancreatic secretion after irradiation in this case clearly suggests a cause and effect relationship and that irradiation of the pancreas may be a useful treatment of pancreatIC ascites, particularly when surgery is inadvisable or impossible.

Clinical correlates of acute right ventricular infarction in acute inferior myocardial infarction.

Hiccups complicating myocardial infarction.

HICCUPS occurring with acute myocardial infarction indicate an extremely grave prognosis and patients afflicted with this distressing complication die.

[Hiccups during acute myocardial infarction].

Hiccups as sole presenting symptom of myocardial infarction.

  • N. S. Gilbert
  • Medicine
    The Journal of the Florida Medical Association. Florida Medical Association
  • 1958

Correlation between symptomatology and site of acute myocardial infarction.

[Singultus: indication of an atypical myocardial infarct?].

Persistent hiccuping in acute myocardial infarction--report of a case.

[A rare initial symptom of myocardial infarct: hiccup].