HiCPlotter integrates genomic data with interaction matrices

  title={HiCPlotter integrates genomic data with interaction matrices},
  author={Kadir Caner Akdemir and Lynda Chin},
  booktitle={Genome Biology},
Metazoan genomic material is folded into stable non-randomly arranged chromosomal structures that are tightly associated with transcriptional regulation and DNA replication. Various factors including regulators of pluripotency, long non-coding RNAs, or the presence of architectural proteins have been implicated in regulation and assembly of the chromatin architecture. Therefore, comprehensive visualization of this multi-faceted structure is important to unravel the connections between nuclear… CONTINUE READING
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