Hexosamine Biosynthesis Is a Possible Mechanism Underlying Hypoxia’s Effects on Lipid Metabolism in Human Adipocytes

@inproceedings{ORourke2013HexosamineBI,
  title={Hexosamine Biosynthesis Is a Possible Mechanism Underlying Hypoxia’s Effects on Lipid Metabolism in Human Adipocytes},
  author={Robert W. O’Rourke and Kevin Anthony Meyer and Garen D. Gaston and Ashley E. White and Carey N Lumeng and Daniel L Marks},
  booktitle={PloS one},
  year={2013}
}
INTRODUCTION Hypoxia regulates adipocyte metabolism. Hexosamine biosynthesis is implicated in murine 3T3L1 adipocyte differentiation and is a possible underlying mechanism for hypoxia's effects on adipocyte metabolism. METHODS Lipid metabolism was studied in human visceral and subcutaneous adipocytes in in vitro hypoxic culture with adipophilic staining… CONTINUE READING