Hexachlorocyclohexane-induced testicular dysfunction in rats.

Weanling male albino rats were fed 100, 750 and 1500 p.p.m. of technical HCH for 90 days. There was marked testicular atrophy with reduced tubule size and spermatogenetic arrest at 1500 p.p.m. Histochemically, there was accumulation of cholesterol-positive lipids in the Sertoli cells and the Leydig cells of the atrophied testis and biochemical estimation… CONTINUE READING