Hex-1, a gene unique to filamentous fungi, encodes the major protein of the Woronin body and functions as a plug for septal pores.

@article{Tenney2000Hex1AG,
  title={Hex-1, a gene unique to filamentous fungi, encodes the major protein of the Woronin body and functions as a plug for septal pores.},
  author={Kristen Tenney and Ian Hunt and James A. Sweigard and June I. Pounder and Carolyn McClain and Emma Jean Bowman and Barry J. Bowman},
  journal={Fungal genetics and biology : FG & B},
  year={2000},
  volume={31 3},
  pages={205-17}
}
We have identified a gene, named hex-1, that encodes the major protein in the hexagonal crystals, or Woronin bodies, of Neurospora crassa. Analysis of a strain with a null mutation in the hex-1 gene showed that the septal pores in this organism were not plugged when hyphae were damaged, leading to extensive loss of cytoplasm. When grown on agar plates containing sorbose, the hex-1(-) strain showed extensive lysis of hyphal tips. The HEX-1 protein was predicted to be 19,125 Da. Analysis of the N… CONTINUE READING

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