Heterotypic lymphoproliferative response in pigs vaccinated with foot-and-mouth disease virus. Involvement of isolated capsid proteins.

@article{Siz1992HeterotypicLR,
  title={Heterotypic lymphoproliferative response in pigs vaccinated with foot-and-mouth disease virus. Involvement of isolated capsid proteins.},
  author={Juan Carlos S{\'a}iz and Ana Rodr{\'i}guez and Manuel Gonz{\'a}lez and Fermin Alonso and Francisco Sobrino},
  journal={The Journal of general virology},
  year={1992},
  volume={73 ( Pt 10)},
  pages={2601-7}
}
The in vitro viral lymphoproliferative response of pigs vaccinated against foot-and-mouth disease virus (FMDV) has been characterized. Peripheral blood mononuclear cells from immunized animals up to 1 year post-immunization (p.i.) showed a time-dependent FMDV-specific response, as assayed by virus-specific cellular blastogenesis. The optimum viral concentration decreased with time (around 20 weeks p.i.), and the response was faster and weaker. Lymphoproliferation appeared to be mainly due to… CONTINUE READING

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