Heterotypic Humoral and Cellular Immune Responses following Norwalk Virus Infection

@article{Lindesmith2009HeterotypicHA,
  title={Heterotypic Humoral and Cellular Immune Responses following Norwalk Virus Infection},
  author={L. Lindesmith and Eric Donaldson and J. Le{\'o}n and C. Moe and J. Frelinger and R. Johnston and D. Weber and R. Baric},
  journal={Journal of Virology},
  year={2009},
  volume={84},
  pages={1800 - 1815}
}
ABSTRACT Norovirus immunity is poorly understood as the limited data available on protection after infection are often contradictory. In contrast to the more prominent GII noroviruses, GI norovirus infections are less frequent in outbreaks. The GI noroviruses display very complex patterns of heterotypic immune responses following infection, and many individuals are highly susceptible to reinfection. To study the immune responses and mechanisms of GI.1 persistence, we built structural models and… Expand
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References

SHOWING 1-10 OF 105 REFERENCES
Multivalent norovirus vaccines induce strong mucosal and systemic blocking antibodies against multiple strains.
  • 138
Herd Immunity to GII.4 Noroviruses Is Supported by Outbreak Patient Sera
  • 104
  • PDF
Norovirus pathogenesis: mechanisms of persistence and immune evasion in human populations
  • 238
  • PDF
Mechanisms of GII.4 Norovirus Persistence in Human Populations
  • 475
  • PDF
Cellular and Humoral Immunity following Snow Mountain Virus Challenge
  • 242
  • PDF
Primary High-Dose Murine Norovirus 1 Infection Fails To Protect from Secondary Challenge with Homologous Virus
  • 35
  • PDF
Epitopes in the P2 domain of norovirus VP1 recognized by monoclonal antibodies that block cell interactions.
  • 95
Human susceptibility and resistance to Norwalk virus infection
  • 897
Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus
  • 221
  • Highly Influential
  • PDF
...
1
2
3
4
5
...