Heterotopic ossification as a complication of acetabular fracture. Prophylaxis with low-dose irradiation.

@article{Bosse1988HeterotopicOA,
  title={Heterotopic ossification as a complication of acetabular fracture. Prophylaxis with low-dose irradiation.},
  author={M. Bosse and A. Poka and C. Reinert and F. Ellwanger and R. Slawson and E. McDevitt},
  journal={The Journal of bone and joint surgery. American volume},
  year={1988},
  volume={70 8},
  pages={
          1231-7
        }
}
In a retrospective review of thirty-seven patients who had operative treatment for thirty-eight complex acetabular fractures, postoperative low-dose irradiation was administered to seventeen patients (eighteen fractures) to suppress heterotopic ossification. All of the patients had been operated on through either an extended iliofemoral incision or a modified extended iliofemoral incision. The prophylactic radiation was administered using a low-dose protocol; most of the patients received 1,000… Expand
Prevention of heterotopic bone formation after acetabular fracture fixation by single-dose radiation therapy: a preliminary report.
TLDR
It is concluded that single, low-dose radiation therapy is a safe and effective method for prevention of HO in the postoperative acetabular fracture patient and is as effective as previously reported multidose regimens. Expand
Indomethacin Compared with Localized Irradiation for the Prevention of Heterotopic Ossification Following Surgical Treatment of Acetabular Fractures
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Both local radiation therapy and indomethacin were found to provide effective prophylaxis against heterotopic ossification following surgical treatment of acetabular fractures through a posterior or extensile approach. Expand
Low-dose irradiation and indomethacin prevent heterotopic ossification after acetabular fracture surgery.
TLDR
The combination therapy proved very effective; 44 fractures showed no heterotopic ossification and ten showed Brooker class I, and the functional results were good and there were no complications of this therapy. Expand
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TLDR
Indomethacin and single-dose radiation therapy are both safe and effective for the prevention of HO after operation for acetabular fractures, and radiation therapy is approximately 200 times more expensive than indometHacin therapy at this institution and has other risks. Expand
Indomethacin and heterotopic ossification in acetabular fractures: A prospective cohort study of the effect indomethacin has on the incidence and severity of heterotopic ossification
TLDR
It is confirmed that indomethacin reduces the incidence and severity of HO in acetabular fracture surgery and is more effective if started pre-operatively. Expand
The role of post-operative radiation in the prevention of heterotopic ossification in patients with post-traumatic acetabular fracture.
TLDR
Radiation therapy has again proven itself to be an excellent surgical adjunct to prevent heterotopic ossification, this time in traumatic acetabular fracture patients. Expand
Indometacin as prophylaxis for heterotopic ossification after the operative treatment of fractures of the acetabulum.
TLDR
Based on these results, it cannot recommend the routine use of indometacin for prophylaxis against heterotopic ossification after isolated fractures of the acetabulum. Expand
Heterotopic ossification in rehabilitation patients who have had internal fixation of an acetabular fracture.
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High-energy trauma patients often have multiple injuries and are frequently seen by a physiatrist following their acute care, and the importance of adequate prophylaxis for heterotopic ossification is discussed. Expand
Does indomethacin reduce heterotopic bone formation after operations for acetabular fractures?: A prospective randomised study
TLDR
Indomethacin was therefore not effective in preventing ectopic bone formation after surgery for acetabular fractures and there was a significant association of male gender with volume of HO using a non-parametric analysis of variance. Expand
Does indomethacin reduce heterotopic bone formation after operations for acetabular fractures? A prospective randomised study.
TLDR
Indomethacin was therefore not effective in preventing ectopic bone formation after surgery for acetabular fractures and there was a significant association of male gender with volume of HO using a non-parametric analysis of variance. Expand
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EDITORS]: Pelvic and Acetabular Fractures
  • Thorofare, New Jersey,
  • 1986
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