Heterosynaptic structural plasticity on local dendritic segments of hippocampal CA1 neurons.

@article{Oh2015HeterosynapticSP,
  title={Heterosynaptic structural plasticity on local dendritic segments of hippocampal CA1 neurons.},
  author={Won Chan Oh and Laxmi Kumar Parajuli and Karen Zito},
  journal={Cell reports},
  year={2015},
  volume={10 2},
  pages={162-9}
}
Competition between synapses contributes to activity-dependent refinement of the nervous system during development. Does local competition between neighboring synapses drive circuit remodeling during experience-dependent plasticity in the cerebral cortex? Here, we examined the role of activity-mediated competitive interactions in regulating dendritic spine structure and function on hippocampal CA1 neurons. We found that high-frequency glutamatergic stimulation at individual spines, which leads… CONTINUE READING
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