Heterosynaptic facilitation in neurones of the abdominal ganglion of Aplysia depilans.

@article{Kandel1965HeterosynapticFI,
  title={Heterosynaptic facilitation in neurones of the abdominal ganglion of Aplysia depilans.},
  author={Eric R. Kandel and Ladislav Tauc},
  journal={The Journal of Physiology},
  year={1965},
  volume={181}
}
The cellular mechanisms whereby a neural network undergoes a longlasting change in its response to a given stimulus, when the latter is repeated or combined with other stimuli, are still mainly unexplored. An important beginning has been the investigation of the effects of physiological use and disuse and of tetanic nerve stimulation on the monosynaptic spinal reflex (Eccles, 1958, 1964). This work has shown that limited potentialities for synaptic plasticity can be demonstrated, even in this… 

Mechanism of heterosynaptic facilitation in the giant cell of the abdominal ganglion of Aplysia depilans.

The analysis of the mechanism underlying this heterosynaptic facilitation in the giant cell was facilitated by the reliable identification of the right upperquadrant giant cell, as well as its large size.

Mechanisms of heterosynaptic facilitation in molluscan neurons

It is concluded that DA or NA may control the HSF intensity and duration under natural conditions of the nervous system in the molluscs.

Characteristics of heterosynaptic facilitation in giant neurons of the cerebral ganglion of Planorbis corneus

Experiments on giant neurons of the cerebral ganglion of the molluskPlanorbis corneus showed that heterosynaptic facilitation even if evoked by a single uncombined stimulation of the pallial nerve,

Contribution of a humoral factor to postsynaptic sensitization in heterosynaptic facilitation

It was deduced that the postsynaptic membrane of the giant neuron makes a significant contribution to heterosynaptic facilitation of the sensitization of n-cholinergic receptors.

System of synaptic influences on neurons of the neocortex in the presence of a conditioned reflex

The interaction of heterogeneous synaptic inputs of neocortical neurons during the effectuation of a conditioned reflex (CR) is reviewed, and hypotheses are advanced concerning the operation of this

Effects of monoamines on heterosynaptic facilitation in giant neurons of Planorbis corneus

The effects of noradrenaline and dopamine on heterosynaptic facilitation (HSF) were investigated during experiments on giant identified neurons from the cerebral ganglion of the freshwater

Beitrag zum Problem der heterosynaptischen Facilitation in Aplysia californica

Heterosynaptic facilitation of single neurons in the central nervous system of Aplysia can be repeated virtually indefinitely, provided sufficient time is allowed for recovery between the trials, and changes occur in some of the test units towards higher responsiveness to subsequent paired stimulation.
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References

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Mechanism of heterosynaptic facilitation in the giant cell of the abdominal ganglion of Aplysia depilans.

The analysis of the mechanism underlying this heterosynaptic facilitation in the giant cell was facilitated by the reliable identification of the right upperquadrant giant cell, as well as its large size.

AN ELECTROPHYSIOLOGICAL STUDY OF THE ANATOMICAL RELATIONS OF TWO GIANT NERVE CELLS IN APLYSIA DEPILANS.

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  • Biology
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Evidence was obtained that under normal conditions of excitability, the spike originates at some distance from the soma in an axonal region with a higher excitability surpassing that of the surrounding membranes.

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The application of acetylcholine by perfusion or local injection to different central neurones of the mollusc Aplysia depilans always produced one of the two following reactions: cells of one type, conventionally designated by us as H-neurones, are hyperpolarized and inhibited by the drug.

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