Heterosynaptic facilitation in neurones of the abdominal ganglion of Aplysia depilans.

@article{Kandel1965HeterosynapticFI,
  title={Heterosynaptic facilitation in neurones of the abdominal ganglion of Aplysia depilans.},
  author={Eric R. Kandel and Ladislav Tauc},
  journal={The Journal of Physiology},
  year={1965},
  volume={181}
}
The cellular mechanisms whereby a neural network undergoes a longlasting change in its response to a given stimulus, when the latter is repeated or combined with other stimuli, are still mainly unexplored. An important beginning has been the investigation of the effects of physiological use and disuse and of tetanic nerve stimulation on the monosynaptic spinal reflex (Eccles, 1958, 1964). This work has shown that limited potentialities for synaptic plasticity can be demonstrated, even in this… Expand
Time course of repetitive heterosynaptic facilitation in Aplysia californica.
TLDR
Support is presented for the view that some of the test neurons can be exhausted by stimulation of the priming nerve alone and for the effect of pairing in the fresh preparation or the first test response after a long period of rest on the exhaustion of the HSF. Expand
Mechanism of heterosynaptic facilitation in the giant cell of the abdominal ganglion of Aplysia depilans.
TLDR
The analysis of the mechanism underlying this heterosynaptic facilitation in the giant cell was facilitated by the reliable identification of the right upperquadrant giant cell, as well as its large size. Expand
Mechanisms of heterosynaptic facilitation in molluscan neurons
TLDR
It is concluded that DA or NA may control the HSF intensity and duration under natural conditions of the nervous system in the molluscs. Expand
Characteristics of heterosynaptic facilitation in giant neurons of the cerebral ganglion of Planorbis corneus
Experiments on giant neurons of the cerebral ganglion of the molluskPlanorbis corneus showed that heterosynaptic facilitation even if evoked by a single uncombined stimulation of the pallial nerve,Expand
Contribution of a humoral factor to postsynaptic sensitization in heterosynaptic facilitation
TLDR
It was deduced that the postsynaptic membrane of the giant neuron makes a significant contribution to heterosynaptic facilitation of the sensitization of n-cholinergic receptors. Expand
The role of the interstimulus interval in heterosynaptic facilitation in Aplysia californica.
TLDR
Since in psychological conditioning experiments ISIs of the same magnitude have been found to be optimal, this paper further allows indicating another similarity between HSF and behavioral conditioning. Expand
System of synaptic influences on neurons of the neocortex in the presence of a conditioned reflex
  • V. M. Storozhuk
  • Chemistry, Medicine
  • Neuroscience and Behavioral Physiology
  • 2005
The interaction of heterogeneous synaptic inputs of neocortical neurons during the effectuation of a conditioned reflex (CR) is reviewed, and hypotheses are advanced concerning the operation of thisExpand
Effects of monoamines on heterosynaptic facilitation in giant neurons of Planorbis corneus
The effects of noradrenaline and dopamine on heterosynaptic facilitation (HSF) were investigated during experiments on giant identified neurons from the cerebral ganglion of the freshwaterExpand
The generation and modulation of endogenous rhythmicity in the Aplysia bursting pacemaker neurone R15.
TLDR
The account of the burst cycle emerges from a consideration of currents experimentally measurable in R15, and it is shown that axonal action potential conduction and hence cell topology play a crucial role in the generation of somal activity. Expand
Beitrag zum Problem der heterosynaptischen Facilitation in Aplysia californica
Summary1. Heterosynaptic facilitation (H.S.F.) of single neurons in the central nervous system of Aplysia can be repeated virtually indefinitely, provided sufficient time is allowed for recoveryExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 44 REFERENCES
Mechanism of heterosynaptic facilitation in the giant cell of the abdominal ganglion of Aplysia depilans.
TLDR
The analysis of the mechanism underlying this heterosynaptic facilitation in the giant cell was facilitated by the reliable identification of the right upperquadrant giant cell, as well as its large size. Expand
Aspects of the organization of central nervous pathways in Aplysia depilans.
TLDR
A great variety has been shown in the extent to which afferent stimulation may affect the whole or part of the central nervous system and the great multiplicity in the pathways whereby this is achieved. Expand
AN ELECTROPHYSIOLOGICAL STUDY OF THE ANATOMICAL RELATIONS OF TWO GIANT NERVE CELLS IN APLYSIA DEPILANS.
TLDR
An hypothesis is suggested to account for the presence of the cell bodies of the RGC and LGC in two different ganglia, despite the similarities in branching of their axons, despite their different locations in the adult. Expand
SENSITIVITY OF NEURONES IN APLYSIA TO TEMPORAL PATTERN OF ARRIVING IMPULSES.
TLDR
Nerve cells were found to exhibit a sensitivity to timing that issued from elementary functional attributes that would be biologically advantageous, especially in areas of sensory convergence, for it provides an additional coding parameter complementing mean frequency modulation. Expand
Problems of Plasticity and Organization at Simplest Levels of Mammalian Central Nervous System
  • J. Eccles
  • Biology, Medicine
  • Perspectives in biology and medicine
  • 1958
TLDR
Investigations indicate that the central transmitters are liberated from the synaptic vesicles in the presynaptic terminals, and act in the same manner as transmitters at peripheral junctions, and there are at least two, one being acetylcholine, and probably several more central excitatory transmitter substances. Expand
Site of Origin and Propagation of Spike in the Giant Neuron of Aplysia
  • L. Tauc
  • Biology, Medicine
  • The Journal of general physiology
  • 1962
TLDR
Evidence was obtained that under normal conditions of excitability, the spike originates at some distance from the soma in an axonal region with a higher excitability surpassing that of the surrounding membranes. Expand
Presynaptic and post‐synaptic events during post‐tetanic potentiation and facilitation in the avian ciliary ganglion
TLDR
The experiments to be reported here indicate that both PTP and facilitation of the synaptic potential can occur without any change in the configuration of the presynaptic spike or in the resting membrane potential of the nerve terminal. Expand
Cholinergic Transmission Mechanisms for both Excitation and Inhibition in Molluscan Central Synapses
TLDR
The application of acetylcholine by perfusion or local injection to different central neurones of the mollusc Aplysia depilans always produced one of the two following reactions: cells of one type, conventionally designated by us as H-neurones, are hyperpolarized and inhibited by the drug. Expand
The Physiology of Synapses
  • J. Eccles
  • Biology
  • Springer Berlin Heidelberg
  • 1964
TLDR
This chapter discusses the development of ideas on the synapse, the ionic mechanism generating the inhibitory postsynaptic potential, and the trophic and plastic properties of synapses. Expand
Structure and Function.
THE aim of this stately book is to show how the various types of animals have solved the fundamental problems of life, and how their struc-ture is to be interpreted in terms of their functions andExpand
...
1
2
3
4
5
...