Heterologous protein expression in Hypocrea jecorina: a historical perspective and new developments.

@article{Singh2015HeterologousPE,
  title={Heterologous protein expression in Hypocrea jecorina: a historical perspective and new developments.},
  author={Arjun Singh and Larry E. Taylor and Todd A. Vander Wall and Jeffrey G. Linger and Michael E. Himmel and Kara Podkaminer and William S. Adney and Stephen R Decker},
  journal={Biotechnology advances},
  year={2015},
  volume={33 1},
  pages={142-154}
}
Hypocrea jecorina, the sexual teleomorph of Trichoderma reesei, has long been favored as an industrial cellulase producer, first utilizing its native cellulase system and later augmented by the introduction of heterologous enzymatic activities or improved variants of native enzymes. Expression of heterologous proteins in H. jecorina was once considered difficult when the target was an improved variant of a native cellulase. Developments over the past nearly 30 years have produced strains… CONTINUE READING

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