Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product.

@article{Kim2012HeterologousPO,
  title={Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product.},
  author={Eun Ji Kim and Jong Hyun Lee and Hyukjae Choi and Alban R. Pereira and Yeon Hee Ban and Y Yoo and Eunji Kim and Je Won Park and David H. Sherman and William H Gerwick and Yeo Joon Yoon},
  journal={Organic letters},
  year={2012},
  volume={14 23},
  pages={5824-7}
}
Heterologous expression of the barbamide biosynthetic gene cluster, obtained from the marine cyanobacterium Moorea producens, in the terrestrial actinobacterium Streptomyces venezuelae, resulted in the production of a new barbamide congener 4-O-demethylbarbamide, demonstrating the potential of this approach for investigating the assembly and tailoring of complex marine natural products. 

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