Heterologous expression of pyruvate decarboxylase in Geobacillus thermoglucosidasius


Expression of a pyruvate decarboxylase (Pdc) pathway in metabolically versatile thermophilic bacteria could create novel ethanologenic organisms, but no suitable thermostable Pdc is available. We have demonstrated that Pdc from Zymomonas mobilis can be expressed in an active form in Geobacillus thermoglucosidasius at up to 52°C, while expression of Pdc… (More)
DOI: 10.1007/s10529-008-9698-1

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