Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice

Abstract

Idiopathic pulmonary fibrosis is a very common interstitial lung disease derived from chronic inflammatory insults, characterized by massive scar tissue deposition that causes the progressive loss of lung function and subsequent death for respiratory failure. Bleomycin is used as the standard agent to induce experimental pulmonary fibrosis in animal models… (More)
DOI: 10.3389/fimmu.2017.00199

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Cite this paper

@inproceedings{Stellari2017HeterologousMM, title={Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice}, author={Fabio Franco Stellari and Francesca Ruscitti and Daniela Pompilio and Francesca Ravanetti and Giulia Tebaldi and Francesca Macchi and Andrea Elizabeth Verna and Gino Villetti and Gaetano Donofrio}, booktitle={Front. Immunol.}, year={2017} }