Heterologous Expression of Human IL-29 ( IFN-λ 1 ) in Iranian Lizard Leishmania

@inproceedings{Taromchi2013HeterologousEO,
  title={Heterologous Expression of Human IL-29 ( IFN-λ 1 ) in Iranian Lizard Leishmania},
  author={Amir Hossein Taromchi and Bahram Kazemi and Sanaz Mahmazi and Mojgan Bandehpour},
  year={2013}
}
Background: Interferons with different functions such as antiviral, antiproliferative and immunomodulatory actions are effective medications for a number of diseases. One of these new interferons (IFNs) is Interleukin-29 (IL-29) belongs to the family of IFN-λ has antiviral activity and its potent in accompanying with IFN-α in treatment of HCV infection has been evaluated (clinical trial phase II). Recombinant IL-29 has been previously produced in multiple expression systems but in this study we… CONTINUE READING

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