Heterogenous nuclear ribonucleoprotein Q increases protein expression from HIV-1 Rev-dependent transcripts

@inproceedings{Vincendeau2012HeterogenousNR,
  title={Heterogenous nuclear ribonucleoprotein Q increases protein expression from HIV-1 Rev-dependent transcripts},
  author={Michelle Vincendeau and Daniel M Nagel and Jara Kerstin Brenke and Ruth Brack-Werner and Kamyar Hadian},
  booktitle={Virology Journal},
  year={2012}
}
Heterogenous nuclear ribonucleoproteins (hnRNPs) control many processes of the gene expression machinery including mRNA transcription, splicing, export, stability and translation. Recent data show interaction of the HIV-1 Rev regulatory protein with a subset of hnRNP proteins, that includes hnRNP Q, suggesting that hnRNPs can contribute to regulation of HIV-1 gene expression by Rev. In this work we address the effect of hnRNP Q on Rev-dependent gene expression. We show that hnRNP Q… CONTINUE READING
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