Heterogeneous resistance to vancomycin in Staphylococcus epidermidis, Staphylococcus haemolyticus and Staphylococcus warneri clinical strains: characterisation of glycopeptide susceptibility profiles and cell wall thickening.

@article{Nunes2006HeterogeneousRT,
  title={Heterogeneous resistance to vancomycin in Staphylococcus epidermidis, Staphylococcus haemolyticus and Staphylococcus warneri clinical strains: characterisation of glycopeptide susceptibility profiles and cell wall thickening.},
  author={Ana Paula Ferreira Nunes and L{\'u}cia M Teixeira and Natalia Lopes Pontes P{\'o}voa Iorio and Carla Calleg{\'a}rio Reis Bastos and Leila de Sousa Fonseca and Tha{\"i}s Cristina Baeta Soares Souto-Padr{\'o}n and K{\'a}tia Regina Netto dos Santos},
  journal={International journal of antimicrobial agents},
  year={2006},
  volume={27 4},
  pages={307-15}
}
The population analysis profile (PAP) method as well as analysis of autolytic activity and cellular ultrastructure by transmission electron microscopy (TEM) were used to characterise Staphylococcus epidermidis, Staphylococcus haemolyticus and Staphylococcus warneri clinical strains with reduced susceptibility to glycopeptides. All strains showed heterogeneous profiles to vancomycin and teicoplanin by the PAP method. Subpopulations that grew in the presence of high concentrations of each drug… CONTINUE READING

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