Heterogeneous prevalence of mutations in KRAS, BRAF, and PIK3CA genes among Sardinian patients with colorectal carcinoma.

Abstract

e14100 Background: In addition to KRAS mutations, it has been suggested that either BRAF or PIK3CA mutations might also confer tumor resistance to EGFR-targeted antibodies in colorectal cancer (CRC). However, conflicting data are being generated regarding the incidence of BRAF and PIK3CA mutations in different populations as well as the impact on response… (More)

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Cite this paper

@article{Palomba2011HeterogeneousPO, title={Heterogeneous prevalence of mutations in KRAS, BRAF, and PIK3CA genes among Sardinian patients with colorectal carcinoma.}, author={Grazia Palomba and Maria Colombino and Antonio Silverio Contu and Bruno Massidda and Giovanni Baldino and Maria Teresa Ionta and Antonio Pazzola and Francesca Capelli and Vittorio Trova and Tito Sedda and Antonio Farris and Francesco Tanda and Mario Budroni and Giovannella Palmieri and Antonio Cossu}, journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology}, year={2011}, volume={29 15_suppl}, pages={e14100} }