Heterogeneous oxygen partial pressure and pH distribution in C3H mouse mammary adenocarcinoma.

@article{Vaupel1981HeterogeneousOP,
  title={Heterogeneous oxygen partial pressure and pH distribution in C3H mouse mammary adenocarcinoma.},
  author={Peter Vaupel and Stan Frinak and H I Bicher},
  journal={Cancer research},
  year={1981},
  volume={41 5},
  pages={2008-13}
}
Severe disturbances in microcirculation during advanced phases of tumor growth lead to restrictions of convective and diffusive transport. In addition, an inhomogeneous distribution of transport conditions develops, resulting in insufficient and heterogeneous substrate supply and an inadequate drainage of wastes. Polarographic measurements of the local… CONTINUE READING