Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases.

@article{Schauber2006HeterogeneousEO,
  title={Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases.},
  author={Juergen Schauber and Daniel Rieger and Frank Weiler and Jan Wehkamp and Matthias Eck and Klaus Fellermann and Wolfgang M Scheppach and Richard L Gallo and Eduard F Stange},
  journal={European journal of gastroenterology & hepatology},
  year={2006},
  volume={18 6},
  pages={615-21}
}
BACKGROUND Inflammatory bowel diseases (IBDs) are characterized by a breakdown of colon epithelial barrier function. Antimicrobial peptides like cathelicidins are molecules of the innate immune system located at epithelial surfaces. Cathelicidins influence microbial growth and inflammation and may play a role in IBD. In this study, the expression of human cathelicidin hCAP18/LL-37 was investigated in the intestinal mucosa from patients suffering from ulcerative colitis or Crohn's disease… CONTINUE READING

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