Heterogeneous expression and association of beta-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray.

Abstract

Most colorectal carcinomas (CRCs) arise from adenomas through an archetypal pathogenic pathway, the adenoma-carcinoma-metastasis sequence. Aberrant expression of beta-catenin, p16, E-cadherin and c-myc appears to have played important roles in the development and/or progression of CRC, but their precise distribution pattern and associations in different… (More)

Topics

Cite this paper

@article{Xie2003HeterogeneousEA, title={Heterogeneous expression and association of beta-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray.}, author={Dan Xie and Jonathan Shuntong Sham and Wei-fen Zeng and Han-liang Lin and Li-hong Che and Hui-xi Wu and J. Wen and Yan Fang and Liang Hu and X. Guan}, journal={International journal of cancer}, year={2003}, volume={107 6}, pages={896-902} }