Heterogeneous enantioselective hydrogenation over cinchona alkaloid modified platinum: mechanistic insights into a complex reaction.

@article{Brgi2004HeterogeneousEH,
  title={Heterogeneous enantioselective hydrogenation over cinchona alkaloid modified platinum: mechanistic insights into a complex reaction.},
  author={Thomas B{\"u}rgi and Alfons Baiker},
  journal={Accounts of chemical research},
  year={2004},
  volume={37 11},
  pages={909-17}
}
Modification of a metal surface by a strongly adsorbed chiral organic molecule has proven to be an interesting strategy for heterogeneous chiral catalysis. Platinum chirally modified by cinchona alkaloids, successfully applied for the enantioselective hydrogenation of alpha-ketoesters, is probably the most prominent catalyst based on this concept. Despite… CONTINUE READING