Heterogeneous distribution of angiotensin I-converting enzyme (CD143) in the human and rat vascular systems: vessel, organ and species specificity.

@article{Metzger2011HeterogeneousDO,
  title={Heterogeneous distribution of angiotensin I-converting enzyme (CD143) in the human and rat vascular systems: vessel, organ and species specificity.},
  author={Roman Patrick Metzger and Folker Ernst Franke and Rainer Bohle and François Alhenc-G{\'e}las and Sergei M Danilov},
  journal={Microvascular research},
  year={2011},
  volume={81 2},
  pages={206-15}
}
Angiotensin I-converting enzyme (kininase II, ACE, CD143) availability is a determinant of local angiotensin and kinin concentrations and physiological actions. Limited information is available on ACE synthesis in peripheral vascular beds. We studied the distribution of ACE along the human and rat vascular tree, and determined whether the enzyme was uniformly distributed in all endothelial cells (EC) or if differences occurred among vessels and organs. The distribution of ACE was assessed by… CONTINUE READING
Highly Cited
This paper has 204 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

204 Citations

050100'12'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 204 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…