Heterogeneous cardiac sympathetic denervation and decreased myocardial nerve growth factor in streptozotocin-induced diabetic rats: implications for cardiac sympathetic dysinnervation complicating diabetes.

@article{Schmid1999HeterogeneousCS,
  title={Heterogeneous cardiac sympathetic denervation and decreased myocardial nerve growth factor in streptozotocin-induced diabetic rats: implications for cardiac sympathetic dysinnervation complicating diabetes.},
  author={Helena Schmid and Lisa Ann Forman and Xuesong Cao and Philip S Sherman and Martin J. Stevens},
  journal={Diabetes},
  year={1999},
  volume={48 3},
  pages={603-8}
}
Heterogeneous myocardial sympathetic denervation complicating diabetes has been invoked as a factor contributing to sudden unexplained cardiac death. In subjects with diabetic autonomic neuropathy (DAN), distal left ventricular (LV) denervation contrasts with preservation of islands of proximal innervation, which exhibit impaired vascular responsiveness. The aims of this study were to determine whether this heterogeneous pattern of myocardial sympathetic denervation occurs in a rat model of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

Modeling and imaging cardiac sympathetic neurodegeneration in Parkinson's disease.

American journal of nuclear medicine and molecular imaging • 2014
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…