Heterogeneous bioenergetic behaviour of subsarcolemmal and intermyofibrillar mitochondria in fed and fasted rats

@article{Mollica2005HeterogeneousBB,
  title={Heterogeneous bioenergetic behaviour of subsarcolemmal and intermyofibrillar mitochondria in fed and fasted rats},
  author={Maria Pia Mollica and Lill{\`a} Lionetti and Raffaella Crescenzo and Elvira D’Andrea and Marialuisa Ferraro and Giovanna Liverini and Susanna Iossa},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2005},
  volume={63},
  pages={358-366}
}
Abstract.This study was designed to examine energetic behaviour of skeletal muscle subsarcolemmal and intermyofibrillar mitochondrial populations. The data show that subsarcolemmal mitochondria exhibited a lower degree of coupling and efficiency than intermyofibrillar ones, and can therefore be considered less efficient at producing ATP. In addition, subsarcolemmal mitochondria showed an increased sensitivity to palmitate-induced uncoupling, in line with high adenine nucleotide translocator… CONTINUE READING
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