Heterogeneous Nuclear Ribonucleoprotein B 1 as a New Marker of Early Detection for Human Lung Cancers 1

@inproceedings{Sueoka1999HeterogeneousNR,
  title={Heterogeneous Nuclear Ribonucleoprotein B 1 as a New Marker of Early Detection for Human Lung Cancers 1},
  author={Eisaburo Sueoka and Yuri Goto and Naoko Sueoka and Yasuko Kai and Tomoko Kozu and Hirota Fujiki},
  year={1999}
}
Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is an RNA binding protein that is required for maturation of mRNA precursor. Tockman et al.previously reported that hnRNP A2/B1 with a Mr of 31,000 is overexpressed from the early clinical stage of human lung cancer (M. S. Tockman et al., J. Clin. Oncol., 6: 1685–1693, 1988). However, when hnRNP A2/B1mRNA and hnRNP B1mRNA were separately studied, we found unique evidence thathnRNP B1mRNA, which is a splicing variant of hnRNP A2 mRNA, was… CONTINUE READING

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