Heterogeneous CD8+ T Cell Migration in the Lymph Node in the Absence of Inflammation Revealed by Quantitative Migration Analysis

@inproceedings{Banigan2015HeterogeneousCT,
  title={Heterogeneous CD8+ T Cell Migration in the Lymph Node in the Absence of Inflammation Revealed by Quantitative Migration Analysis},
  author={Edward J. Banigan and Tajie H. Harris and David A. Christian and Christopher A. Hunter and Andrea J. Liu},
  booktitle={PLoS Computational Biology},
  year={2015}
}
The three-dimensional positions of immune cells can be tracked in live tissues precisely as a function of time using two-photon microscopy. However, standard methods of analysis used in the field and experimental artifacts can bias interpretations and obscure important aspects of cell migration such as directional migration and non-Brownian walk statistics. Therefore, methods were developed for minimizing drift artifacts, identifying directional and anisotropic (asymmetric) migration, and… CONTINUE READING
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