Heterogeneity of tight junctions in the thick ascending limb.

Abstract

Renal tubular transport mechanisms are optimized to be energy efficient and tailored to local gradients and transport rates. The combined transcellular action of ion channels, transporters, and pumps, together with the paracellular pathway, enables kidney function. Monogenetic diseases and mouse models indicate that both trans- and paracellular proteins can… (More)
DOI: 10.1111/nyas.13400

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