Heterogeneity of systemic inflammatory responses to periodontal therapy.

  title={Heterogeneity of systemic inflammatory responses to periodontal therapy.},
  author={Jan H Behle and Michael H Sedaghatfar and Ryan T. Demmer and Dana L Wolf and Romanita S. Celenti and Moritz Kebschull and Paul B Belusko and Miriam Herrera-Abreu and Evanthia Lalla and Panos N. Papapanou},
  journal={Journal of clinical periodontology},
  volume={36 4},
AIMS We investigated the effect of comprehensive periodontal therapy on the levels of multiple systemic inflammatory biomarkers. MATERIAL AND METHODS Thirty patients with severe periodontitis received comprehensive periodontal therapy within a 6-week period. Blood samples were obtained at: 1-week pre-therapy (T1), therapy initiation (T2), treatment completion (T3), and 4 weeks thereafter (T4). We assessed the plasma concentrations of 19 biomarkers using multiplex assays, and serum IgG… CONTINUE READING

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