Heterogeneity of spina bifida.

  title={Heterogeneity of spina bifida.},
  author={Birgitte M. Blatter and A B Lafeber and Paul W J Peters and Nel Roeleveld and Andr{\'e} L. M. Verbeek and Fons J. M. Gabre{\"e}ls},
  volume={55 4},
Splitting birth defects into dysmorphologically homogeneous groups might improve the ability to detect a genetic risk factor or teratogenic exposure. With regard to spina bifida, recent studies suggest that etiologic heterogeneity exists within the group of spina bifida, although exogenous risk factors have been sparsely evaluated for subgroups. In the present study, 210 spina bifida patients were classified into relatively homogeneous groups, based on retrospective information on appearance… CONTINUE READING

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