Heterogeneity of solubilized muscarinic cholinergic receptors: binding and hydrodynamic properties.

@article{Baron1985HeterogeneityOS,
  title={Heterogeneity of solubilized muscarinic cholinergic receptors: binding and hydrodynamic properties.},
  author={Bruce Baron and Moshe Gavish and Mordechai Sokolovsky},
  journal={Archives of biochemistry and biophysics},
  year={1985},
  volume={240 1},
  pages={281-96}
}
Previous studies have described the conversion, after detergent solubilization, of the multiple populations of membrane-bound muscarinic agonist binding sites to a population of uniform affinity. This paper describes the solubilization of at least two receptor species, distinct in their agonist binding characteristics, which are capable of interconversion by transition metal ions. This finding enabled a more detailed examination of the molecular properties and regional differences of brain… CONTINUE READING