Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma.

@article{Mote2000HeterogeneityOP,
  title={Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma.},
  author={Patricia A. Mote and Rosemary L. Balleine and Eileen M McGowan and Christine L. Clarke},
  journal={Human reproduction},
  year={2000},
  volume={15 Suppl 3},
  pages={
          48-56
        }
}
The human progesterone receptor (PR) is expressed as two isoforms, PRA and PRB, which function as ligand-activated transcription factors. In-vitro studies suggest that the isoforms differ functionally and that their relative expression in a target cell may determine the nature and magnitude of response to progesterone. We have shown recently that PRA and PRB are co-expressed in target cells of the human endometrium. The purpose of this study was to investigate the homogeneity of expression of… CONTINUE READING

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