Heterogeneity of presenting features and their relation to treatment outcome in 120 children with T-cell acute lymphoblastic leukemia.

@article{Pui1990HeterogeneityOP,
  title={Heterogeneity of presenting features and their relation to treatment outcome in 120 children with T-cell acute lymphoblastic leukemia.},
  author={Ching-Hon Pui and Frederick G. Behm and Bhuvanesh Singh and Michael J. Schell and Dorothy L. Williams and Gaston K. Rivera and David K. Kalwinsky and John T. Sandlund and William M. Crist and Susana C. Raimondi},
  journal={Blood},
  year={1990},
  volume={75 1},
  pages={174-9}
}
Presenting features of 120 consecutive children with T-cell acute lymphoblastic leukemia (ALL), representing 15% of all patients diagnosed as having ALL during the study period, were analyzed to determine relationships with treatment outcome. Patients' ages ranged from 1.7 to 18.8 years (median, 10.3 years) and their leukocyte counts from 1.7 to 1,070 x 10(9)/L (median, 100 x 10(9)/L). Central nervous system (CNS) leukemia was present in 12.5% of the cases, a mediastinal mass in 61%, and L2… CONTINUE READING
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