Heterogeneity of oxygen delivery impairs oxygen extraction by peripheral tissues: theory.

@article{Walley1996HeterogeneityOO,
  title={Heterogeneity of oxygen delivery impairs oxygen extraction by peripheral tissues: theory.},
  author={Keith R. Walley},
  journal={Journal of applied physiology},
  year={1996},
  volume={81 2},
  pages={885-94}
}
The hypothesis that the distribution of oxygen demand in relation to oxygen supply (dO2/qO2) effects oxygen extraction in peripheral tissues was tested. By using a simple theoretical model, realistic biphasic oxygen consumption-delivery relationships were predicted from dO2/qO2 distributions. Increasing width (relative dispersion) of the dO2/qO2 distribution, indicating mismatch between oxygen demand and supply, nonlinearly decreased the critical oxygen extraction ratio (calculated by using… CONTINUE READING

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