Heterogeneity of mu-opioid receptors as one of the factors sensitive to narcotic analgesics


The concept of the heterogeneity of mu1-opioid receptors has been considered. The morphological differentiation of receptors determined by genetic variations should be considered to be the most important proposition of the concept. Genetic variations are polymorphisms of the mu-opioid receptor gene and the phenomenon of alternative splicing. They variations… (More)
DOI: 10.1134/S2079086413020035


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