Heterogeneity of hyperdiploid (51-67) childhood acute lymphoblastic leukemia.

@article{Raimondi1996HeterogeneityOH,
  title={Heterogeneity of hyperdiploid (51-67) childhood acute lymphoblastic leukemia.},
  author={Susana C. Raimondi and Ching-Hon Pui and Michael L. Hancock and Frederick G. Behm and Leonid V. Filatov and Gaston K. Rivera},
  journal={Leukemia},
  year={1996},
  volume={10 2},
  pages={
          213-24
        }
}
We studied the fully banded chromosomes of 182 children with hyperdiploid (51-67) acute lymphoblastic leukemia (ALL) to better delineate the heterogeneity of this disease subtype. Forty-six percent of the cases had numerical changes exclusively, while the remainder had structural as well as numerical changes. Chromosome 21 was added most often (97% of cases), followed by chromosomes 6 (86%), X (81%), 14 (80%), 4 (76%), 18 (68%), 17 (68%), 10 (56%), 8 (34%) and 5 (26%). Chromosomal… CONTINUE READING

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