Heterogeneity of human peripheral blood eosinophils: variability in cell density and cytotoxic ability in relation to the level and the origin of hypereosinophilia.

@article{Prin1983HeterogeneityOH,
  title={Heterogeneity of human peripheral blood eosinophils: variability in cell density and cytotoxic ability in relation to the level and the origin of hypereosinophilia.},
  author={Lionel Prin and Monique Capron and A. B. Tonnel and Olivier Bl{\'e}try and Andr{\'e} Capron},
  journal={International archives of allergy and applied immunology},
  year={1983},
  volume={72 4},
  pages={336-46}
}
Considerable variations in the distribution of eosinophil populations were revealed by density gradient centrifugation of peripheral blood leukocytes from 14 normal subjects and 31 patients with a transient or persistent hypereosinophilia. Such a purification procedure enabled us to collect in healthy controls, eosinophils (77.1 +/- 15.9% SD purity) with an appreciable cell recovery (21.7 +/- 14.0% SD) in the densest gradients ('normodense' cells). A high degree of purity was obtained in the… CONTINUE READING

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