Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender

@article{Ryoo2011HeterogeneityOG,
  title={Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender},
  author={Hyunju Ryoo and Jiyoung Woo and Younyoung Kim and Chaeyoung Lee},
  journal={European Journal of Human Genetics},
  year={2011},
  volume={19},
  pages={672-675}
}
We examined the genetic associations of previously identified sequence variants with type 2 diabetes mellitus (T2DM) and its potentially genetic heterogeneity by gender in a large-scale cohort. A total of 613 T2DM patients and 8221 control subjects from the Korea Association REsource (KARE) cohort were included in the analysis of genetic association of T2DM with 33 nucleotide polymorphic markers identified by previous studies. The association analysis was further conducted with data partitioned… CONTINUE READING
14 Citations
25 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Implication of genetic variants near SLC 30 A 8 , HHEX , CDKAL 1 , CDKN 2 A / B , IGF 2 BP 2 , FTO , TCF 2 , KCNQ 1 , and WFS 1 in type 2 diabetes in a Chinese population

  • X Han, Y Luo, Q Ren
  • BMC Med Genet
  • 2010

Investigation of type 2 diabetes risk alleles support CDKN 2 A / B , CDKAL 1 , and TCF 7 L 2 as susceptibility genes in a Han Chinese cohort

  • J Wen, T Rönn, A Olsson
  • PLoS One
  • 2010

Association between polymorphisms in SLC 30 A 8 , HHEX , CDKN 2 A / B , IGF 2 BP 2 , FTO , WFS 1 , CDKAL 1 , KCNQ 1 and type 2 diabetes in the Korean population

  • YH Lee, ES Kang, SH Kim
  • J Hum Genet
  • 2008

Common variants in CDKAL 1 , CDKN 2 A / B , IGF 2 BP 2 , SLC 30 A 8 , and HHEX / IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population

  • Y Wu, H Li, RJ Loos
  • Diabetes
  • 2008

Similar Papers

Loading similar papers…