Heterogeneity of gastrointestinal hormones

@article{Rehfeld1979HeterogeneityOG,
  title={Heterogeneity of gastrointestinal hormones},
  author={Jens Frederik Rehfeld},
  journal={World Journal of Surgery},
  year={1979},
  volume={3},
  pages={415-422}
}
The molecular heterogeneity of gastrointestinal hormones is reviewed. The phenomenon of heterogeneity is characteristic of all secreted proteins, including macromolecules like albumin and immunoglobulins, as well as protein and polypeptide hormones. Heterogeneity reflects basal mechanisms involved in ribosomal biosynthesis, posttranslational cleavage and modification, as well as degradation in peripheral tissue of biologically important substances. Thus far, all gastrointestinal hormones have… CONTINUE READING
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