Heterogeneity of colorectal adenomas, the serrated adenoma, and implications for screening and surveillance.

@article{Freeman2008HeterogeneityOC,
  title={Heterogeneity of colorectal adenomas, the serrated adenoma, and implications for screening and surveillance.},
  author={Hugh James Freeman},
  journal={World journal of gastroenterology},
  year={2008},
  volume={14 22},
  pages={3461-3}
}
Current algorithms for screening and surveillance for colon cancer are valuable, but may be limited by the underlying nature of the targeted neoplastic lesions. Although part of the success of adenoma removal relates to interruption of so-called "adenoma-carcinoma sequence", an alternate serrated pathway to colon cancer may pose difficulties with the ultimate results achieved by traditional colonoscopic methods. The endpoint carcinoma in this unique pathway may be derived from a dysplastic… CONTINUE READING