Heterogeneity of brain structural variation and the structural imaging endophenotypes in schizophrenia.

@article{Nenadic2012HeterogeneityOB,
  title={Heterogeneity of brain structural variation and the structural imaging endophenotypes in schizophrenia.},
  author={Igor Nenadic and Christian Gaser and Heinrich Sauer},
  journal={Neuropsychobiology},
  year={2012},
  volume={66 1},
  pages={44-9}
}
Schizophrenia is often assumed to comprise a group of biologically distinct disorders, yet it has been difficult to dissect subgroups using biological markers. We review recent brain imaging morphometry studies addressing the issue of heterogeneity within the diagnostic category of schizophrenia. Studies of subgroups of schizophrenia patients have mostly used either symptom structure or clinical course for the delineation of potentially meaningful subgroups. Studies defining subgroups according… CONTINUE READING