Heterogeneity of a labeled tumor surface protein from a murine lung carcinoma demonstrated by two-dimensional electrophoresis.

Abstract

Heterogeneity of a tumor surface protein (designated TSP-180) has been demonstrated by two-dimensional electrophoresis. Line 1 carcinoma cells derived from a spontaneous alveolar carcinoma of BALB/c mice were labeled externally with 125I by use of lactoperoxidase or metabolically with [3H]-leucine before cell proteins were solubilized with Triton X-100… (More)

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